Despair is a Chaos-based curse spell in Path of Exile 2 that weakens enemy resistance after a short delay, amplifying the effectiveness of all Chaos damage-over-time effects. It excels in DoT-heavy builds and synergizes with ailments like Wither and Poison.
"Curse all targets in an area after a short delay, lowering their Chaos Resistance."
Note: Purchasing this item, you will receive a level 21 Despair gem with 5 Support Sockets.
Path of Exile 2 Despair Features
Item Type: Spell, AoE, Chaos, Duration, Curse
Tier 9 | Level Range: 1–20
Attributes Required: 2–205 Intelligence
Mana Cost: 42–251
Cast Time: 0.70 sec
Effect:
Applies Curse after 1.5 seconds delay
Reduces Chaos Resistance by (-24 to -18)%
Curse radius: 1.5–3.1 metres
Curse duration: 6–7.4 seconds
Quality bonus: up to +10% increased Curse Magnitudes
How to Get Despair in Path of Exile 2
Despair can be acquired via:
Engraving starting with Uncut Skill Gem Tier 9
Level 21 Despair Gem can only be obtained by corrupting a level 20 gem
Use a perfect jeweller's orb to get to 5 sockets before corrupting it for a level 21 Despair gem
Tradeable via player marketplaces
Despair Mechanics & Use
Delayed Application: Curse applies 1.5 seconds after cast, allowing for trap/mines preloading
Resistance Reduction: Lowers Chaos Resistance, boosting all Chaos DoT effects
Duration Scaling: Ideal for prolonged engagements and layering curses
Build Synergy: Works best with Essence Drain, Contagion, Wither, and Poison builds
Curse Radius: Scales with gem level, enabling wide-area debuffing
Recommended Support Gems
Tier 1: Impending Doom, Prolonged Duration I, Heightened Curse
Tier 2: Lifetap, Focused Curse, Abiding Hex
Tier 3: Prolonged Duration II, Decaying Hex, Ritualistic Curse
Tier 4: Efficiency II, Rapid Casting II, Burning Inscription
Path of Exile 2 Despair Mechanic FAQs
1. Does Despair affect enemies with Chaos immunity?
No. Chaos-immune enemies are unaffected by Despair. However, it still applies to targets with high Chaos resistance, making it essential for bypassing partial mitigation.
2. Can Despair be triggered via traps, mines, or totems?
Yes. Despair is fully compatible with trap, mine, and totem setups. The 1.5s delay allows strategic placement before engagement.
3. Does Despair stack with other Chaos resistance reduction effects?
Yes, but only additively. Despair stacks with Withered and other curses, but is subject to curse limit rules unless Hexproof is bypassed.
4. Is the delay affected by cast speed or support gems?
No. The 1.5s delay is fixed and cannot be reduced by cast speed or support gems. However, faster casting allows quicker layering.
5. Does Despair benefit Poison or Wither builds?
Absolutely. Despair amplifies all Chaos DoT sources, making it a cornerstone for Poison, Wither, and hybrid ailment builds.
How to Buy Path of Exile 2 Despair from MMOJUGG
Step 1: Add Despair to your cart. Click “Proceed to Checkout" to fill in your delivery information.
Step 2: Select your server and enter your in-game character name (Not your PoE ID with #). Console players should include PSN ID or Xbox Gamertag.
Step 3: Check out securely with PayPal, Visa, MasterCard, and more.
After purchase, our team will add you in-game, join your party, and deliver the item inside your Hideout. Always verify item details before accepting trades.
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