Path of Exile 2 Lesser Inspiration Rune *5

Lesser Inspiration Rune is a Socketable item used during early-game progression in Path of Exile 2. It provides mana recovery bonuses across weapon and armor types and is commonly used in builds focused on sustained casting and regeneration. Once socketed, it cannot be removed, but it can be replaced with another rune or soul core.

Martial Weapons: Gain 8 Mana per Enemy Killed

Armour: 12% increased Mana Regeneration Rate

Wand or Staff: 16% increased Mana Regeneration Rate

Lesser Inspiration Rune Features

• Item Type: Socketable – Rune

• Function:

  • Martial Weapons: Gain 8 Mana per Enemy Killed

  • Armour: 12% increased Mana Regeneration Rate

  • Wand or Staff: 16% increased Mana Regeneration Rate

• Usable on: Martial Weapons, Armour, Wands, or Staff

• Stack Size: 1 / 10  |  Drop Level: 21  |  Required Level: None

How to Obtain Lesser Inspiration Rune

• Drop Locations:

  • Found as world drops in zones level 21+

• Other Sources:

  • Crafted via Three to One Reforge recipe at the Reforging Bench

    • Recipe: Lesser Inspiration Rune x3 → Inspiration Rune x1

Lesser Inspiration Rune Crafting Synergy & Usage

Lesser Inspiration Rune is ideal for characters seeking consistent mana recovery through regeneration or kill-based triggers. It supports mana-themed builds and offers reliable sustain for both melee and spellcasting playstyles.

• Best Use Cases:

  • Melee builds that frequently kill enemies and benefit from on-kill mana gain

  • Armor-based characters requiring passive mana regeneration

  • Spellcasters needing sustained mana flow for repeated casting

• Crafting Notes:

  • Must be socketed into gear with open Rune sockets

  • Cannot be removed once applied

  • Can be replaced with another rune or soul core since Patch 0.2.0 Dawn of the Hunt

Lesser Inspiration Rune FAQs

How does the Lesser Inspiration Rune compare to other Lesser Runes?

Lesser Inspiration Rune offers both passive and active mana recovery options, making it versatile for builds that rely on frequent casting or enemy kills.

Can I remove a socketed Lesser Inspiration Rune?

No. Once socketed, it cannot be removed. However, it can be overwritten by another rune or soul core.

Can I socket multiple Lesser Inspiration Runes into one item?

Yes. As long as the item has multiple open Rune sockets, each Lesser Inspiration Rune will apply its full effect. The bonuses stack linearly.

Does the kill-based mana gain work with spells?

Yes. As long as the enemy is killed by your character, the mana gain applies regardless of whether the killing blow was melee or spell-based.

What happens when I replace a socketed rune?

The original rune is destroyed. Only unsocketed ones can be reforged or reused.

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