Path of Exile 2 Inspiration Rune

Inspiration Rune is a mid-tier Socketable item in Path of Exile 2, designed to enhance mana recovery for both martial and spellcasting builds. It offers stronger bonuses than its lesser counterpart and is commonly used in sustained combat scenarios where mana flow is critical.

Martial Weapons: Gain 16 Mana per Enemy Killed

Armour: 15% increased Mana Regeneration Rate

Wand or Staff: 20% increased Mana Regeneration Rate

Inspiration Rune Features

• Item Type: Socketable – Rune

• Function:

  • Martial Weapons: Gain 16 Mana per Enemy Killed

  • Armour: 15% increased Mana Regeneration Rate

  • Wand or Staff: 20% increased Mana Regeneration Rate

• Usable on: Martial Weapons, Armour, Wands, or Staff

• Stack Size: 1 / 10  |  Drop Level: 45  |  Required Level: 15

How to Obtain Inspiration Rune

• Drop Locations:

  • Found as world drops in zones level 45+

• Other Sources:

  • Crafted via Three to One Reforge recipe at the Reforging Bench

    • Recipe 1: Lesser Inspiration Rune x3 → Inspiration Rune x1

    • Recipe 2: Inspiration Rune x3 → Greater Inspiration Rune x1

Inspiration Rune Crafting Synergy & Usage

Inspiration Rune is ideal for mid-game builds that require reliable mana sustain through regeneration or kill-based triggers. It supports hybrid playstyles and scales well with both melee and ranged spellcasting.

• Best Use Cases:

  • Melee builds that rely on frequent kills for mana sustain

  • Armor-based characters needing stronger passive regeneration

  • Spellcasters with high mana consumption and limited downtime

• Crafting Notes:

  • Must be socketed into gear with open Rune sockets

  • Cannot be removed once applied

  • Can be replaced with another rune or soul core since Patch 0.2.0 Dawn of the Hunt

Inspiration Rune FAQs

How does Inspiration Rune compare to Lesser Inspiration Rune?

It offers significantly stronger bonuses across all gear types, making it more suitable for mid-game and mana-intensive builds.

Can I overwrite a socketed Inspiration Rune with a Greater version?

Yes. Socketing a Greater Inspiration Rune will destroy the original and apply the new effect.

Does the kill-based mana gain work with AoE or DoT skills?

Yes, as long as the enemy is killed by your character, the effect triggers regardless of skill type.

Can I use multiple Inspiration Runes in one item?

Yes, provided the item has multiple Rune sockets. Effects stack linearly.

Is the rune tradable or stackable?

Yes. Stack size is 1 / 10 and it can be traded freely.

How to Buy Inspiration Rune from MMOJUGG

• Step 1: Add Inspiration Rune to your cart. Click "Proceed to Checkout" to fill in your delivery information.

• Step 2: Select your server and enter your in-game character name. Console players should include PSN ID or Xbox Gamertag.

• Step 3: Checkout securely with PayPal, Visa, MasterCard, and more.

After purchase, our team will add you in-game, join your party, and deliver the item inside your Hideout. Always verify item details before accepting trades.

Why Choose MMOJUGG for Inspiration Rune

• Complete Path of Exile 2 Supply: From basic currency to rare items, we deliver fast and reliably, ensuring your items arrive promptly and securely.

• Advanced Order Management: Track your order status anytime through our Order Track, ensuring you stay updated every step of the way.

• 24/7 Customer Support: Reach us via live chat or email at [email protected]—we're always here to help.

• Secure Payments: Pay with PayPal, Visa, MasterCard, and more—all transactions are secure and protected.

• Refund Policy: 100% satisfaction guaranteed—fast, no-hassle refunds if you have any concerns or feedback.